De-risk your drug development strategy
Pharmath Consulting provides expert quantitative systems pharmacology and PK/PD modeling for pharma and biotech programs. We translate complex mechanistic biology into actionable simulation strategies — helping your team answer the hard questions early, navigate regulatory scrutiny with confidence, and make better decisions at every stage of development.
Over a decade of modeling leadership across Pfizer, Applied BioMath, and Certara — now available as an independent scientific partner.
Services
Our work is tailored to your program's specific questions and stage of development — from early discovery through regulatory submission.
Model-Informed Drug Development (MIDD/MID3)
From trial design to regulatory briefing documents, we build the quantitative modeling and simulation frameworks that support your most critical development decisions — and help you defend them to the FDA.
Mechanistic PK/PD & Quantitative Systems Pharmacology (QSP)
We build mechanistic models grounded in your biology — scaling in complexity from targeted PK/PD analyses to full QSP platforms — to evaluate target feasibility, candidate properties, and dose selection with confidence.
Early Feasibility & Competitive Benchmarking
Before committing resources to a program, we build focused mechanistic models to map the parameter space where your TPP can be achieved — and assess exactly how your molecule stacks up against the competitive landscape.
Disease Progression & Virtual Populations
We model patient variability, disease trajectories, and long-term clinical endpoints to de-risk your phase transitions and build the virtual population frameworks regulators increasingly expect.